Інформація призначена тільки для фахівців сфери охорони здоров'я, осіб,
які мають вищу або середню спеціальну медичну освіту.


Підтвердіть, що Ви є фахівцем у сфері охорони здоров'я.

"Pain. Joints. Spine." 1 (21) 2016

Back to issue

Body mass index — marker of bone mineral density in children with chronic hepatitis B and C

Authors: Kinash M.I., Boyarchuk O.R., Dzyuban L.V., Breznitska M.I., Luchyshyn N.Y., Kubey I.V. - Ternopil State Medical University named after I. Gorbachevsky, Ternopil, Ukraine

Categories: Rheumatology, Traumatology and orthopedics

Sections: Medical forums

print version

The article was published on p. 74-75

 

Osteoporosis (OP) — one of the most pressing current medical and socio-economic problems of society. OP has a special place among the diseases associated with the violation of a metabolic changes in bone tissue (BT). Bone mineral density (BMD), which is formed up to 20 years, determines the factors of risk of Opand osteoporosis fractures in the elderly. There is a need to create favorable conditions for achieving the respective MDBT in childhood and adolescence, the selection of quality criteria for preclinical diagnosis of OP for early detection of metabolic disorders BT.

Aim of this work was to establish the relationship between MDBT in children with chronic hepatitis B and/or C and body mass index (BMI).
Under the supervision were 37 children with chronic hepatitis B and/or C, which were confirmed by using ELISA and PCR. Children’s age ranged from 5 to 15 years. In 59.5 % of patients with chronic hepatitis (CH) was inactive phase of the process, and in 40.5 % — the minimum activity and in all cases it ran in anicteric forms. The boys among the examined were 23 (62.2 %), girls — 14 (37.8 %). All children conducted densitometry study of the first four lumbar vertebras by the densitometer DPX-A company Lunar corporation by a method of dual energy X-ray absorption in a mode «Children». The results of examination were densytograma, and calculated by a computer program sizes (Age Matched, BMC, BMD, Area). The main parameters that define the BMD, is the content of minerals in the examined bone (BMC, g), and the mineral density of bones (VMD g/cm2), the criterion Age Matched, which is expressed as a percentage of age-ethnic and weight regulation (%) and in terms of the standard deviation of the average theoretical rules (Z). Value index Z, according to WHO, from (–1,0 to –2,5) would regard as the initial development of bone changes or osteopenic syndrome of (–2,5 to –2,0) — osteopenia ІІІ degree, from (–2,0 to –1,5) — osteopenia second degree, and from (–1,5 to –1,0) — osteopenia first degree; value Z to (–1,0) consider normal. In dismissing Z less (–2,5) diagnosed with so-called «set OP».
In addition, studying the interdependence of BMI (the ratio of body weight to growth in square of examenated expressed in kg/m2) and BMD.
Reduced BMD, given the value of Z, was diagnosed in 18 (48.7 %) patients, in particular, the degree of I degree of osteopenia — 2.7 %, II degree — 21.7 %, III degree — 10.8 % and OP — in 13.5 % of patients.
In the study in depth osteopenic syndrome surveyed a direct correlation between the values of BMD (r = 0.75), Z (r = 0.63) and the value of BMI.
Body mass index in patients with low BMD (15.84 ± 0.58) kg/m2 was authentically (p < 0,05) lower than in patients with normal bone mineralization (19.30 ± ± 0.62) kg/m2 and in healthy children (23.42 ± 0.53) kg/m2. It was also found authentically (p < 0,05) reduction in body mass index in patients with osteopenia I + II, III degrees and OP against children of the control group and patients with normal bone mineralization. Differences of this indicator depending on sex and activity of CH is not found, but found significant (p < 0,05) differences in values of body mass index between different age groups with low BMD, (14,21 ± 1,06) kg/m2 — children and 5–10 years (18.54 ± 0.55) kg/m2 — in persons 11–15 years, respectively.
In this way, body mass index with a value (15.84 ± 0.58) kg/m2 and below may be one of the diagnostic criteria osteopenic syndrome in children with inaparant and subclinical forms of chronic hepatitis B and/or C.

Similar articles

Bone mineral density, T- and Z-scores in young men with juvenile idiopathic arthritis
Authors: V.V. Povoroznyuk(1), M.B. Dzhus(2)
(1) — State Institution “D.F. Chebotarev Institute of Gerontology of the NAMS Ukraine”, Kyiv, Ukraine
(2) — Bogomolets National Medical University, Kyiv, Ukraine

"Pain. Joints. Spine." Том 7, №4, 2017
Date: 2018.02.13
Categories: Rheumatology, Traumatology and orthopedics
Sections: Clinical researches
The Indicators Bone Metabolism in Fractures of Trochanteric Areas of Femur in Patients with Type 2 Diabetes
Authors: Shymon V.M., Stoyka V.V., Sheregiy A.A., Shymon M.V., Slyvka R.M. - Uzhgorod National University, Uzhgorod, Ukraine
"Pain. Joints. Spine." 2 (18) 2015
Date: 2015.08.14
Categories: Rheumatology, Traumatology and orthopedics
Sections: Medical forums
Frequency and localization of osteoporotic fractures depending on age, bone mineral density  and trabecular bone score in postmenopausal women of Ukrainian cohort
Authors: V. Povoroznyuk, N. Grygorieva, T. Orlyk
State Institution “D.F. Chebotarev Institute of Gerontology of the NAMS of Ukraine”, Kyiv, Ukraine
Ukrainian Scientific Medical Center of Osteoporosis Problems, Kyiv, Ukraine

"Pain. Joints. Spine." Том 8, №2, 2018
Date: 2018.07.27
Categories: Rheumatology, Traumatology and orthopedics
Sections: Clinical researches
Comparison of TBS and FRAX in fracture risk assessment of postmenopausal females with osteopenia
Authors: Kuzma M., Jackuliak P. - Medical Faculty of Comenius University, 5th Department of Internal Medicine, University Hospital, Bratislava, Slovakia; Vanuga P. - National Institute of Endocrinology and Diabetology, Ľubochňa, Slovakia; Killinger Z., Payer J. - Medical Faculty of Comenius University, 5th Department of Internal Medicine, University Hospital, Bratislava, Slovakia
"Pain. Joints. Spine." 1 (21) 2016
Date: 2016.06.01
Categories: Rheumatology, Traumatology and orthopedics
Sections: Medical forums

Back to issue