Інформація призначена тільки для фахівців сфери охорони здоров'я, осіб,
які мають вищу або середню спеціальну медичну освіту.

Підтвердіть, що Ви є фахівцем у сфері охорони здоров'я.

"Pain. Joints. Spine." 1 (21) 2016

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Calcium and vitamin D: the true story

Authors: Reginster J.-Y. - University of Liège, Liège, Belgium

Categories: Rheumatology, Traumatology and orthopedics

Sections: Medical forums

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The article was published on p. 82

 

There is evidence that Calcium and Vitamin D, given in combination, reduce the risk of fractures in the elderly. Based on available data, almost all individuals get sufficient Vitamin D when their blood levels are at, or above 50 nmol/l. Controversial results were observed, in observational studies, regarding Calcium and ischaemic heart disease. Intakes of Calcium above 1400 mg/day, in women, were associated with higher death rates from all causes and cardiovascular diseases but not stroke. Other studies reported an increased risk of myocardial infarction in patients receiving Calcium supplementation but no increase in cardiovascular death. In interventional studies, when appropriate reporting of cardiovascular events was used, no difference was observed between patients receiving Calcium supplements and those who did not. The conclusion of a recent meta-analysis was that, when using events verified by clinical review, hospital record or death certificate, the hypothesis that Calcium supplementation, with or without Vitamin D, increases coronary heart disease or all-cause mortality risk in elderly women, was not supported. 

In summary, whereas one cannot formally exclude that Calcium supplements (without Vitamin D) may be associated with an increase in the risk of myocardial infarction, this risk remains unclear but cardiovascular mortality is unaffected, coronary artery calcification is not accelerated and the risk of stroke is not elevated.   


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