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"Pain. Joints. Spine." 1 (21) 2016

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Diabetes and bone

Authors: Resch Н. - Medical Department II, KH Barmherzige Schwestern, Academic Teaching Hospital MUV, Vienna, Austria

Categories: Rheumatology, Traumatology and orthopedics

Sections: Medical forums

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The article was published on p. 83

 

Osteoporosis and type 2 diabetes share several common features: their incidences are steadily rising and they are of multifactorial etiology. Initially,both diseases are asymptomatic, but in the long run may severely impair the quality of life.Due to the high life expectation of the world population, the incidence, the costs, and the complications of osteoporosis and diabetes mellitus will increase dramatically. While an association of type 1 diabetes with osteoporosis has been established since many years, traditionally type 2 diabetic patients were considered to be protected from fragility fractures. Nevertheless, data accmulated over the past years indicate that also type 2 diabetic patients — even if they have an augmented bone mineral density — are at increased risks of fractures. Most advanced sophisticated analytic methods which allow high resolution assessmant of bone have also added to our knowledge of diabetic caused changes in bone tissue, especially in cortical structures expressed as cortical porosity and also on material level. Furthermore there are some oft he new oral anidiabetic drugs which also can harm bone metabolism. In this review, molecular and clinical findings of diabetic bone disease will be introduced and discussed together with with features of own experience.   


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