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Журнал «» Том 16, №3-4, 2023

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Кардіометаболічні порушення при артеріальній гіпертензії та цукровому діабеті 2-го типу в умовах воєнного часу (огляд літератури)


Резюме

В огляді вітчизняних та закордонних джерел літератури з наукометричної бази PubMed розглядається питання щодо ролі фактора воєнного часу у виникненні низки кардіометаболічних порушень серед хворих групи дуже високого ризику, а саме хворих на артеріальну гіпертензію на тлі цукрового діабету 2-го типу. Авторами наводяться дані щодо нових маркерів кардіометаболічних порушень при поєднаному перебігу цих захворювань, приділяється увага модифікованим факторам ризику серцево-судинних захворювань та їх корекції. Окремо в історичному аспекті розглядається внесок стресу за часів війни, його крайнього прояву — посттравматичного стресового розладу серед військових та цивільних. Акцентується увага на провокуючій ролі фактора воєнного часу у дитинстві щодо формування низки кардіометаболічних зрушень у дорослому віці, розглядається внесок фактора збройного конфлікту в прогресування цих небезпечних захворювань. Наводяться дані щодо поширеності компонентів метаболічного синдрому серед цієї категорії пацієнтів, характеризуються особливості перебігу та еволюції вищенаведених факторів ризику, в тому числі і аліментарних, серед пацієнтів дуже високого ризику за умов воєнного часу, надається характеристика підходів до підвищення інформованості пацієнтів щодо керування своїми захворюваннями.

The review of Ukrainian and foreign literature sources from the scientometric database PubMed addresses the role of the wartime factor in the occurrence of a number of cardiometabolic disorders among patients of a very high risk group, namely, those with hypertension on the background of type 2 diabetes mellitus. The authors provide data on new markers of cardiometabolic disorders in the combined course of these diseases, pay attention to modifiable risk factors of cardiovascular diseases and their correction. The contribution of stress in wartime, its extreme manifestation — post-traumatic stress disorder among soldiers and civilians is considered separately in the historical aspect. Attention is focused on the provoking role of the wartime factor in childhood regarding the formation of a number of cardiometabolic changes in adulthood, the contribution of the armed conflict factor to the progression of these dangerous diseases is considered. Data on the prevalence of the metabolic syndrome components among this category of patients are presented, the features of the course and evolution of the above risk factors, including nutritional ones, among patients at a very high risk in wartime are considered, and the characteristics of approaches to increasing the awareness of patients regarding the management of their diseases are provided.


Ключевые слова

артеріальна гіпертензія; цукровий діабет 2-го типу; кардіометаболічні порушення; стрес; антропометричні показники; ліпідно-вуглеводний гомеостаз; воєнний час; огляд

hypertension; type 2 diabetes mellitus; cardiometabolic disorders; stress; anthropometric indicators; lipid-carbohydrate homeostasis; wartime; review


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