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"Actual Infectology" Том 7, №2, 2019

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Main populations of imuncompetental peripheral blood cells in patients with chronic hepatitis С

Authors: V.D. Moskaliuk, I.V. Balaniuk, M.O. Sokolenko
Bukovinsky State Medical University, Chernivtsi, Ukraine

Categories: Infectious diseases

Sections: Medical forums

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Background. Hepatitis C remains one of the leading problems of intrahospital infectious diseases associated with hemotransfusions, the introduction of blood products, other medical interventions for diagnostic and therapeutic purposes. The target for HCV is hepatocyte, monocytes/macrophages, B-lymphocytes and polymorphonuclear leukocytes. Direct infection of these immunocompetent cells determines the immunological disorders of congenital and adaptive immunity, which are registered in more than half of patients with chronic hepatitis C. Hepatitis C is one of the most dangerous diseases of the liver of viral etiology, the prevalence of which is constantly increasing. According to most infectionists and epidemiologists, today the number ...

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